Dear @AlexanderKroll
I hope that you are doing well.
I was trying to undrestand the process to achieve experimentally confirmed enzyme-substrate pairs.
Please correct me if I am wrong.
In the ESP pipeline, each reaction is associated with a GO term and a reaction ID. You mapped the GO term to UniProt ID and then linked those UniProt IDs to evidence codes. However, I believe this may be problematic, as a single GO term can correspond to multiple UniProt IDs. Is there possibility that it could have incorrectly mapped a UniProt ID (enzyme) to a reaction?
Best Regards
Vahid
Dear @AlexanderKroll
I hope that you are doing well.
I was trying to undrestand the process to achieve experimentally confirmed enzyme-substrate pairs.
Please correct me if I am wrong.
In the ESP pipeline, each reaction is associated with a
GO termand areaction ID. You mapped theGO termtoUniProt IDand then linked thoseUniProt IDsto evidence codes. However, I believe this may be problematic, as a singleGO termcan correspond to multipleUniProt IDs. Is there possibility that it could have incorrectly mapped aUniProt ID(enzyme) to a reaction?Best Regards
Vahid