diff --git a/projects/plugins/jetpack/_inc/client/settings/index.jsx b/projects/plugins/jetpack/_inc/client/settings/index.jsx
index d1d1a5f1e6ea..5f694e383ff2 100644
--- a/projects/plugins/jetpack/_inc/client/settings/index.jsx
+++ b/projects/plugins/jetpack/_inc/client/settings/index.jsx
@@ -1,5 +1,7 @@
 import { GlobalNotices, ThemeProvider } from '@automattic/jetpack-components';
 import { __, sprintf } from '@wordpress/i18n';
+import { search } from '@wordpress/icons';
+import { EmptyState, Stack } from '@wordpress/ui';
 import { Component } from 'react';
 import { connect } from 'react-redux';
 import { useLocation } from 'react-router';
@@ -13,6 +15,7 @@ import SearchableModules from 'searchable-modules';
 import Security from 'security';
 import Sharing from 'sharing';
 import { isModuleActivated as isModuleActivatedSelector } from 'state/modules';
+import { hasAnyMatchingModule as hasAnyMatchingModuleSelector } from 'state/search';
 import Traffic from 'traffic';
 import Writing from 'writing';
 import { FEATURE_JETPACK_EARN } from '../lib/plans/constants';
@@ -29,6 +32,7 @@ class Settings extends Component {
 			siteRawUrl,
 			blogID,
 			userCanManageModules,
+			hasAnyMatchingModule,
 		} = this.props;
 		const { pathname } = location;
 		const commonProps = {
@@ -36,19 +40,28 @@ class Settings extends Component {
 			rewindStatus,
 			userCanManageModules,
 		};
+		const showEmptySearchState = !! searchTerm && ! hasAnyMatchingModule;
 
 		return (
 			<ThemeProvider>
 				<div className="jp-settings-container">
-					<div className="jp-no-results">
-						{ searchTerm
-							? sprintf(
-									/* translators: %s: a search term entered in search form. */
-									__( 'No search results found for %s', 'jetpack' ),
-									searchTerm
-							  )
-							: __( 'Enter a search term to find settings or close search.', 'jetpack' ) }
-					</div>
+					{ showEmptySearchState && (
+						<Stack justify="center" className="jp-settings__empty-search-results">
+							<EmptyState.Root>
+								<EmptyState.Visual>
+									<EmptyState.Icon icon={ search } />
+								</EmptyState.Visual>
+								<EmptyState.Title>{ __( 'No matching settings', 'jetpack' ) }</EmptyState.Title>
+								<EmptyState.Description>
+									{ sprintf(
+										/* translators: %s: a search term entered in search form. */
+										__( 'No search results found for %s', 'jetpack' ),
+										searchTerm
+									) }
+								</EmptyState.Description>
+							</EmptyState.Root>
+						</Stack>
+					) }
 					<Security
 						siteAdminUrl={ siteAdminUrl }
 						siteRawUrl={ siteRawUrl }
@@ -114,5 +127,6 @@ class Settings extends Component {
 export default connect( state => {
 	return {
 		isModuleActivated: module => isModuleActivatedSelector( state, module ),
+		hasAnyMatchingModule: hasAnyMatchingModuleSelector( state ),
 	};
 } )( props => <Settings { ...props } location={ useLocation() } /> );
diff --git a/projects/plugins/jetpack/_inc/client/settings/style.scss b/projects/plugins/jetpack/_inc/client/settings/style.scss
index 098bf5ecad31..ebf35410258c 100644
--- a/projects/plugins/jetpack/_inc/client/settings/style.scss
+++ b/projects/plugins/jetpack/_inc/client/settings/style.scss
@@ -110,13 +110,16 @@
 		width: 100%;
 	}
 
-	.jp-no-results {
-		display: none;
-		font-size: rem.convert(14px);
-		line-height: 1.5;
-
-		&:last-of-type {
-			display: inherit;
+	.jp-settings__empty-search-results {
+		margin-block: rem.convert(64px);
+
+		// @wordpress/ui zeros margins on EmptyState.Title/Description inside
+		// @layer wp-ui-components, but unlayered admin styles (core + Jetpack)
+		// take precedence and reintroduce h2/p margins. Reset them here so the
+		// component renders with its intended tight spacing.
+		h2,
+		p {
+			margin: 0;
 		}
 	}
 
diff --git a/projects/plugins/jetpack/_inc/client/state/search/reducer.js b/projects/plugins/jetpack/_inc/client/state/search/reducer.js
index 243d84b26bf6..cef58a89cfe9 100644
--- a/projects/plugins/jetpack/_inc/client/state/search/reducer.js
+++ b/projects/plugins/jetpack/_inc/client/state/search/reducer.js
@@ -64,3 +64,18 @@ export function isModuleFound( state, module ) {
 			.indexOf( currentSearchTerm.toLowerCase() ) > -1
 	);
 }
+
+/**
+ * Returns whether any module matches the current search term.
+ *
+ * @param {object} state - Global state tree
+ * @return {boolean}      True only when there is an active search term and at least one module matches it.
+ */
+export function hasAnyMatchingModule( state ) {
+	if ( ! getSearchTerm( state ) ) {
+		return false;
+	}
+
+	const items = state.jetpack?.modules?.items ?? {};
+	return Object.values( items ).some( item => item?.module && isModuleFound( state, item.module ) );
+}
diff --git a/projects/plugins/jetpack/_inc/client/state/search/test/selectors.js b/projects/plugins/jetpack/_inc/client/state/search/test/selectors.js
index 176ed1da2eff..370bdc04f8bc 100644
--- a/projects/plugins/jetpack/_inc/client/state/search/test/selectors.js
+++ b/projects/plugins/jetpack/_inc/client/state/search/test/selectors.js
@@ -1,4 +1,4 @@
-import { isModuleFound } from '../index';
+import { hasAnyMatchingModule, isModuleFound } from '../index';
 
 describe( 'Module found selector', () => {
 	let state = {};
@@ -69,3 +69,41 @@ describe( 'Module found selector', () => {
 		);
 	} );
 } );
+
+describe( 'hasAnyMatchingModule selector', () => {
+	const buildState = ( searchTerm, items ) => ( {
+		jetpack: {
+			modules: { items },
+			search: { searchTerm },
+		},
+	} );
+
+	const items = {
+		photon: {
+			module: 'photon',
+			name: 'Photon',
+			description: 'Serve images from the WordPress.com CDN.',
+		},
+		protect: {
+			module: 'protect',
+			name: 'Protect',
+			description: 'Prevent brute-force login attacks.',
+		},
+	};
+
+	test( 'returns false when the search term is empty', () => {
+		expect( hasAnyMatchingModule( buildState( '', items ) ) ).toBe( false );
+	} );
+
+	test( 'returns false when the modules state has not loaded yet', () => {
+		expect( hasAnyMatchingModule( buildState( 'photon', undefined ) ) ).toBe( false );
+	} );
+
+	test( 'returns true when at least one module matches the search term', () => {
+		expect( hasAnyMatchingModule( buildState( 'brute-force', items ) ) ).toBe( true );
+	} );
+
+	test( 'returns false when no module matches the search term', () => {
+		expect( hasAnyMatchingModule( buildState( 'asdfqwerty', items ) ) ).toBe( false );
+	} );
+} );
diff --git a/projects/plugins/jetpack/changelog/jpprod-105-show-empty-state-message-on-settings-screen b/projects/plugins/jetpack/changelog/jpprod-105-show-empty-state-message-on-settings-screen
new file mode 100644
index 000000000000..40aa3b904ab6
--- /dev/null
+++ b/projects/plugins/jetpack/changelog/jpprod-105-show-empty-state-message-on-settings-screen
@@ -0,0 +1,4 @@
+Significance: patch
+Type: bugfix
+
+Settings: Show an empty state when search returns no matching settings.