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TaxaLevel LMM #1

@mnoguera

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@mnoguera

To develop 330_*.Rmd file analysis:

Taxa level LMM

The main purpose of this script is to extract signla from Linear-Mixed-Models(LMM) from longitudinal designs of data. For each Taxa, at a tax_level, we'll run a LMM through the longitudinal dimension and either, rank taxa according to their longitudinal increase/decreas or to the highest differences between a group variable in cat_var.

Try different data transformation approaches:

  • Relative abudnaces(RA)
  • raw counts, with previous rarefaction at a certain number of reads, using metaphlan_counts object
  • clr transformed data for counts, using microbiome::transform()

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