sequence.gb

LOCUS       HUMINSTHIG             12565 bp    DNA     linear   PRI 06-JAN-1995
DEFINITION  Homo sapiens tyrosine hydroxylase (TH) gene, 3' end; insulin (INS)
            gene, complete cds; insulin-like growth factor 2 (IGF2) gene, 5'
            end.
ACCESSION   L15440
VERSION     L15440.1
KEYWORDS    insulin; insulin-like growth factor 2; tyrosine hydroxylase.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 12565)
  AUTHORS   Lucassen,A.M., Julier,C., Beressi,J.P., Boitard,C., Froguel,P.,
            Lathrop,M. and Bell,J.I.
  TITLE     Susceptibility to insulin dependent diabetes mellitus maps to a 4.1
            kb segment of DNA spanning the insulin gene and associated VNTR
  JOURNAL   Nat. Genet. 4 (3), 305-310 (1993)
   PUBMED   8358440
FEATURES             Location/Qualifiers
     source          1..12565
                     /organism="Homo sapiens"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:9606"
                     /map="11p15.5"
     gene            1..1482
                     /gene="TH"
     exon            <1..141
                     /gene="TH"
                     /number=13
     intron          142..977
                     /gene="TH"
                     /number=13
     exon            978..1482
                     /gene="TH"
                     /note="label: exon14"
                     /number=14
     misc_feature    1484..4246
                     /note="intergenic sequence between tyrosine hydroxylase
                     and insulin; spacer"
     repeat_region   3396..3887
                     /standard_name="INS 5' VNTR"
                     /rpt_type=tandem
     exon            4247..4662
                     /gene="INS"
                     /product="insulin"
                     /note="INS (SWISS: P01308); G00-119-349"
     gene            join(4485..4662,5458..5603)
                     /gene="INS"
     CDS             join(4485..4662,5458..5603)
                     /gene="INS"
                     /note="INS (SWISS: P01308)"
                     /codon_start=1
                     /product="insulin"
                     /protein_id="AAA59179.1"
                     /db_xref="GDB:G00-119-349"
                     /translation="MALWMRLLPLLALLALWGPDPAAAFVNQHLCGSHLVEALYLVCG
                     ERGFFYTPKTRREAEVGQVELGGGPGAGSLQPLALEGSLQKRGIVEQCCTSICSLYQL
                     ENYCN"
     intron          4663..5457
                     /note="INS (SWISS: P01308); G00-119-349; does not fit
                     consensus"
     misc_feature    5604..7079
                     /note="intergenic spacer between insulin and insulin-like
                     growth factor 2, including INS 3' UTR."
     gene            7080..7192
                     /gene="IGF2"
     exon            7080..7192
                     /gene="IGF2"
                     /note="IGF2 (SWISS: P01344); G00-119-331; label: 5'_UTR"
                     /number=1
     intron          7193..12564
                     /note="does not fit consensus"
     repeat_region   11745..12564
                     /rpt_family="ALU"
ORIGIN      
        1 ctgccagcac tgcctgtctg aggagcctga gattcgggcc ttcgaccctg aggctgcggc
       61 cgtgcagccc taccaagacc agacgtacca gtcagtctac ttcgtgtctg agagcttcag
      121 tgacgccaag gacaagctca ggtgggctag gctgctaggg caagcccccc atggtgcccc
      181 caaactgggc cagccaggcc ttccttctgg ccttgagcag ggctggacct gtgagcccag
      241 gtcacagatg agaaaaccga cccctggttg cagcagcccc cacacagcag ggacaccatc
      301 cgtgagaagg actccagcgt ctgggagggg cagacctaca ggactggggc tgctgggtgg
      361 ccgggtcaag gccagtcttg gaggtgctga cagagcctga gctttgtgag gacgtcctgt
      421 ggaacctgtc ccggccccct gccctgggat ggggagaagt cagggggata gacagagtca
      481 aggtggggga cagggcggga gtggggtccc cagggctggg ggcctttggt gcagtgacca
      541 gagtgtcagg agaggggagc aaagccctct agcctcatcc tcataaaagg tctcatcatt
      601 ttccctccag cctcttatgc actgggaaac tgaggccagg ggctatgttg ccagcggaca
      661 ggggtgctga attccaccca caggcttagg gatatggtca aggaaagctt cctggaggag
      721 gcccagtgga ggttcaggga gggatggggt gcccggcagt ctctagtgga aaaggcgcct
      781 agcctatctc ccccatgaac cccctcaccc agccctggaa gaggcctcag tgtcccgcct
      841 gtgaccagtt ggctcagaaa agccctggga gctctgagcc actgtgaagg tggaaacgcg
      901 gcccctggcc tcccctctcc tggaggctgc agactctgcc cgccagttga cgagggctct
      961 gccgctctcc tccccaggag ctatgcctca cgcatccagc gccccttctc cgtgaagttc
     1021 gacccgtaca cgctggccat cgacgtgctg gacagccccc aggccgtgcg gcgctccctg
     1081 gagggtgtcc aggatgagct ggacaccctt gcccatgcgc tgagtgccat tggctaggtg
     1141 cacggcgtcc ctgagggccc ttcccaacct cccctggtcc tgcactgtcc cggagctcag
     1201 gccctggtga ggggctgggt cccgggtgcc ccccatgccc tccctgctgc caggctccca
     1261 ctgcccctgc acctgcttct cagcgcaaca gctgtgtgtg cccgtggtga ggttgtgctg
     1321 cctgtggtga ggtcctgtcc tggctcccag ggtcctgggg gctgctgcac tgccctccgc
     1381 ccttccctga cactgtctgc tgccccaatc accgtcacaa taaaagaaac tgtggtctct
     1441 acacctgcct ggccccacat ctgtgccaca gagacagacc ctgggatcct cagactccca
     1501 cacccccacc ccagcctcac tcagaggttt cgccctggcc tccttcctcc tctgggagat
     1561 ggctggccgc cctggccagg cagctggccc ctccgggcct ggtttccccg ctcaccctga
     1621 ggccccgccc agctctgagc cccaagcagc tccagaggct cgggcaccct ggccgagctg
     1681 ccccatctcc gtggggtgcc ctcccaaggt ggggagccac gtgacagtgg gagggcctct
     1741 ctcaggcctg gaagggagca ggggtcacaa actgtgctgg ctgggggtgg tctcagaggt
     1801 gggcctgcag gcctaaccct ccctgctgac agggctccca gcccttgaga gaaacaggga
     1861 tggaggaaca gctgccctga tgccctcacc cacccggagc aggccctgcg aaccaagggg
     1921 aacctcagtg tggcccccag catgtgtgct gatggggagg gtctggctga gctggtgccc
     1981 aggcagatgg tctgggcctg tctccccagc gaggcaggat gggggctgga tttcagactc
     2041 tgtaagatgc ccctggctta ctcgaggggc ctagacattg ccctccagag agagcaccca
     2101 acaccctcca ggcttgaccg gccagggtgt ccccttccta ccttggagag agcagcccca
     2161 gggcatcctg cagggggtgc tgggacacca gctggccttc aaggtctctg cctccctcca
     2221 gccaccccac tacacgctgc tgggatcctg gatctcagct ccctggccga caacactggc
     2281 aaactcctac tcatccacga aggccctcct gggcatggtg gtccttccca gcctggcagt
     2341 ctgttcctca cacaccttgt tagtgcccag cccctgaggt tgcagctggg ggtgtctctg
     2401 aagggctgtg agcccccagg aagccctggg gaagtgcctg ccttgcctcc ccccggccct
     2461 gccagcgcct ggctctgccc tcctacctgg gctcccccca tccagcctcc ctccctacac
     2521 actcctctca aggaggcacc catgtcctct ccagctgccg ggcctcagag cactgtggcg
     2581 tcctggggca gccaccgcat gtcctgctgt ggcatggctc agggtggaaa gggcggaagg
     2641 gaggggtcct gcagatagct ggtgcccact accaaacccg ctcggggcag gagagccaaa
     2701 ggctgggtgt gtgcagagcg gccccgagag gttccgaggc tgaggccagg gtgggacata
     2761 gggatgcgag gggccggggc acaggatact ccaacctgcc tgcccccatg gtctcatcct
     2821 cctgcttctg ggacctcctg atcctgcccc tggtgctaag aggcaggtaa ggggctgcag
     2881 gcagcagggc tcggagccca tgccccctca ccatgggtca ggctggacct ccaggtgcct
     2941 gttctgggga gctgggaggg ccggaggggt gtaccccagg ggctcagccc agatgacact
     3001 atgggggtga tggtgtcatg ggacctggcc aggagagggg agatgggctc ccagaagagg
     3061 agtgggggct gagagggtgc ctggggggcc aggacggagc tgggccagtg cacagcttcc
     3121 cacacctgcc cacccccaga gtcctgccgc cacccccaga tcacacggaa gaatgaggtc
     3181 cgagtggcct gctgaggact tgctgcttgt ccccaggtcc ccaggtcatg ccctccttct
     3241 gccaccctgg ggagctgagg gcctcagctg gggctgctgt cctaaggcag ggtgggaact
     3301 aggcagccag cagggagggg acccctccct cactcccact ctcccacccc caccaccttg
     3361 gcccatccat ggcggcatct tgggccatcc gggactgggg acaggggtcc tggggacagg
     3421 ggtccgggga cagggtcctg gggacagggg tgtggggaca ggggtctggg gacaggggtg
     3481 tggggacagg ggtgtgggga caggggtctg gggacagggg tgtggggaca ggggtccggg
     3541 gacaggggtg tggggacagg ggtctgggga caggggtgtg gggacagggg tgtggggaca
     3601 ggggtctggg gacaggggtg tggggacagg ggtcctgggg acaggggtgt ggggacaggg
     3661 gtgtggggac aggggtgtgg ggacaggggt gtggggacag gggtcctggg gataggggtg
     3721 tggggacagg ggtgtgggga caggggtccc ggggacaggg gtgtggggac aggggtgtgg
     3781 ggacaggggt cctggggaca ggggtctgag gacaggggtg tgggcacagg ggtcctgggg
     3841 acaggggtcc tggggacagg ggtcctgggg acaggggtct ggggacagca gcgcaaagag
     3901 ccccgccctg cagcctccag ctctcctggt ctaatgtgga aagtggccca ggtgagggct
     3961 ttgctctcct ggagacattt gcccccagct gtgagcaggg acaggtctgg ccaccgggcc
     4021 cctggttaag actctaatga cccgctggtc ctgaggaaga ggtgctgacg accaaggaga
     4081 tcttcccaca gacccagcac cagggaaatg gtccggaaat tgcagcctca gcccccagcc
     4141 atctgccgac ccccccaccc cgccctaatg ggccaggcgg caggggttga caggtagggg
     4201 agatgggctc tgagactata aagccagcgg gggcccagca gccctcagcc ctccaggaca
     4261 ggctgcatca gaagaggcca tcaagcaggt ctgttccaag ggcctttgcg tcaggtgggc
     4321 tcagggttcc agggtggctg gaccccaggc cccagctctg cagcagggag gacgtggctg
     4381 ggctcgtgaa gcatgtgggg gtgagcccag gggccccaag gcagggcacc tggccttcag
     4441 cctgcctcag ccctgcctgt ctcccagatc actgtccttc tgccatggcc ctgtggatgc
     4501 gcctcctgcc cctgctggcg ctgctggccc tctggggacc tgacccagcc gcagcctttg
     4561 tgaaccaaca cctgtgcggc tcacacctgg tggaagctct ctacctagtg tgcggggaac
     4621 gaggcttctt ctacacaccc aagacccgcc gggaggcaga ggacctgcag ggtgagccaa
     4681 ccgcccattg ctgcccctgg ccgcccccag ccaccccctg ctcctggcgc tcccacccag
     4741 catgggcaga agggggcagg aggctgccac ccagcagggg gtcaggtgca cttttttaaa
     4801 aagaagttct cttggtcacg tcctaaaagt gaccagctcc ctgtggccca gtcagaatct
     4861 cagcctgagg acggtgttgg cttcggcagc cccgagatac atcagagggt gggcacgctc
     4921 ctccctccac tcgcccctca aacaaatgcc ccgcagccca tttctccacc ctcatttgat
     4981 gaccgcagat tcaagtgttt tgttaagtaa agtcctgggt gacctggggt cacagggtgc
     5041 cccacgctgc ctgcctctgg gcgaacaccc catcacgccc ggaggagggc gtggctgcct
     5101 gcctgagtgg gccagacccc tgtcgccagc ctcacggcag ctccatagtc aggagatggg
     5161 gaagatgctg gggacaggcc ctggggagaa gtactgggat cacctgttca ggctcccact
     5221 gtgacgctgc cccggggcgg gggaaggagg tgggacatgt gggcgttggg gcctgtaggt
     5281 ccacacccag tgtgggtgac cctccctcta acctgggtcc agcccggctg gagatgggtg
     5341 ggagtgcgac ctagggctgg cgggcaggcg ggcactgtgt ctccctgact gtgtcctcct
     5401 gtgtccctct gcctcgccgc tgttccggaa cctgctctgc gcggcacgtc ctggcagtgg
     5461 ggcaggtgga gctgggcggg ggccctggtg caggcagcct gcagcccttg gccctggagg
     5521 ggtccctgca gaagcgtggc attgtggaac aatgctgtac cagcatctgc tccctctacc
     5581 agctggagaa ctactgcaac tagacgcagc ctgcaggcag ccccacaccc gccgcctcct
     5641 gcaccgagag agatggaata aagcccttga accagccctg ctgtgccgtc tgtgtgtctt
     5701 gggggccctg ggccaagccc cacttcccgg cactgttgtg agcccctccc agctctctcc
     5761 acgctctctg ggtgcccaca ggtgccaacg ccggccaggc ccagcatgca gtggctctcc
     5821 ccaaagcggc catgcctgtt ggctgcctgc tgcccccacc ctgtggctca gggtccagta
     5881 tgggagcttc gggggtctct gaggggccag ggatggtggg gccactgaga agtgacttct
     5941 tgttcagtag ctctggactc ttggagtccc cagagacctt gttcaggaaa gggaatgaga
     6001 acattccagc aattttcccc ccacctagcc ctcccaggtt ctatttttag agttatttct
     6061 gatggagtcc ctgtggaggg aggaggctgg gctgagggag ggggtcctgc agggcggggg
     6121 gctgggaagg tggggagagg ctgccgagag ccacccgcta tccccagctc tgggcagccc
     6181 cgggacagtc acacaccctg gcctcgcggc ccaagctggc agccgtctgc agccacagta
     6241 tgccagccca ggtccagcca gacacctgag ggacccactg gtgccttgga ggaagcagga
     6301 gagaggtcag atggcaccat gagctggggc aggtgcaggg accgtggcag cacctggcag
     6361 ggcctcagaa cccatgcctt gggcaccccg gccatgaggc cctgaggatt gcagcccaag
     6421 agaagcaggg aacgccaggg ccacaggggc agagaccagg gccagggtcc ccctgcagcc
     6481 ccttagccca ccccctccca gtaagcaggg ctgcttggct ggcttccttt gctacagacc
     6541 tgctgctcac ccagaagggc ccacgggccc tggtgacaag gtcgttgtgg ctccaggtcc
     6601 ttgggggtcc tgacacagag cctcttctgc agcacccctg aggacagggt ggctccgctg
     6661 ggcacccagc ctagtgggca gacgagaacc taggggctgc ctgggcctac tgtggcctgg
     6721 gaggtcagcg ggtgacccta gctaccctgt ggctgggcca gtctgcctgc cacccaggcc
     6781 aaaccaatct gcacctttcc tgagagctcc acccagggct gggctgggga tggctgggcc
     6841 tggggctggc atgggctgtg gctgcagacc actgccagct tgggcctcga ggccaggagc
     6901 tcaccctcca gctggggacc tggccactgg ggcagccctg ttcctgaagc tctgagctca
     6961 ccccttcccc atgaccacat cagcccccct ccacccagag atgtcacagc ccccagctag
     7021 ccccgcctcc agagtggggg ccaaggctgg gcaggcgggt ggacggccgg acactggccc
     7081 cggaagagga gggaggcggt ggctgggatc ggcagcagcc gtccatggga acacccagcc
     7141 ggccccactc gcacgggtag agacaggggc gccctgctgg agctgaggta tgtgagctcg
     7201 cgcgggctgg gccaaagcgg ggcccggtgg gccgctggga ggctgcccac cagtcagcca
     7261 tcggccaagc tgttgccctg gctgaccctg atggccaaca aggccgtagg gagtgatggg
     7321 cagaggccct tctgggaggg gagggtcagt gctctgtggg ggaccgtgtg ttggagtgga
     7381 gggcagcagg aggagccctt tggtgtccag ggactcctgg agctgcccca gccttccagg
     7441 acttgcaggg cagctggcac tggctggtgc tgggggctga ggagtgtctt ttgaggggcc
     7501 aaattttctg tgacttctgt cctgggggac ctctgacctg aggcctcagg agagggcaag
     7561 gccgcccacc caaaagagat gcagccatgg ttcgcggtgc cctcggctgc cctgggccag
     7621 agctggggct agctttcacc ttgttgagac ccaggactct gtcccccaag cctgtcttcg
     7681 ccagcgcctt gaccccaccc ctcatatact gtgtcctgga aaacgtggac acgggagacc
     7741 acagccaggg cgaggtatcg cccctccatc cccccaggcc caatgagaag cagttggcca
     7801 aggtgatcca ggtggcagag gcagcatcag acccagtctc ctgtcaggca ccaccttggg
     7861 tgccggtccc cagatgccct ggcggggagt gtgcatgctc ccggaggccc ccaggtcacc
     7921 ccatgtgagc caggcccaca gagcttggct ctgcaatgcc tgctgggctg ctgccatgct
     7981 ccaccccttc tgggaagcta aaagacagcc cttcagtgtc cagagacctg cctggccttg
     8041 gagcctgggt ttcacatgcc caccgggctg gcaggggcac tcagctgcct ccagccccgg
     8101 cggtcaccct ggcattgggt ccatctaact gctccccagt cacaaggcag ctgctcccca
     8161 agtctcccca aacctgctgg cccctctaga agcctctgtc cattcctgga ggaccgaggg
     8221 cagcctgcat gccatcccgc acacagcctt ctgtctggca tcctgccttc acacatgctg
     8281 cacagggagg aaactcttat accacattcc ttaagcagag actgaagcct ggagccaagg
     8341 cacatggcac gtgctcccac ccacccagga cacactgcgg tgtggctgcc tccaggctgg
     8401 ccccctagat tgcgtctgct cctggcatgg ataactggcg cctttgcctg gccgttgggg
     8461 cagtgtttgc cttcccctgt cggcagcaaa tatttactgt cctccgtctc caggactctc
     8521 caggcctgag cagaccccgg ggggatgagt gtggactcag cggtgctgag ggtagccccc
     8581 tgcccttcgg gtcctggtgc ccagcagggg tccagcccag ggaagagact gaggccagga
     8641 caggcagtgt ttaagcctga gtttctggga aaggtagccc tgggcagaac ttgggccgaa
     8701 cgttggccag tgtctctctc cagccaggct gtgaggtgac tgtttccagg atgggcacct
     8761 ttccacaccc agcaatgtgg ccaggagccg ccattcacgg gtgcgaccag cagatggcat
     8821 cagagcctca cttttgatgc actccggcca ccagccacgg gtccaggttc tggccaccac
     8881 ccagggtctg agcagctgca tcctgcccct gccgggcact cccggggctg tggggcctgt
     8941 gggggccctg ccagacactc ttgggggctg tggggggccc tgccaggcac tcccagggac
     9001 tatgggggac tgtgggggcc tgctgggcac tctgaagggc atggggctta ggaatgagag
     9061 gagctgtctg atgatgatgg tgggggtact gcagaggccc ccggctgctc aggtccagtc
     9121 tcggccccta agtcaagcct caggccagcc tctcaccagc ctgggctttc tcagagggcc
     9181 gggacaaatg ttctgggtct ctaatattcc aagaaagcct ctggctggac tctgagcccc
     9241 acctgcgagc ccctagaatc acagagagct agggtgagaa gaccaggggg acaccgtcac
     9301 cctcgtcgtg gctgagccca ctgtggccgg tggtggacca ggctgtggcc tttgctgagg
     9361 gtccccaggg cccctggggg ctactgaggc tggaggccag cggtggccag gagggtccct
     9421 ccctcagcca ctcaagccag aaggtcgagt cctggtttct atgtgaggag ggggcttcag
     9481 gggctgggac ctgggggcac cgaagcctgg agctggggtc caggcggctg agggttagtg
     9541 cgttcccacg ctcccctccg ccagcgccgt gaggagaggg aggtccactc tggaaagaat
     9601 gtttgagggg caggggtaga cagggtctgg gaacgcgaga tgacacactg gggtgccgcc
     9661 tccgcacctc cgcccttcct cccactattg tttctggctc ggccacagga acagcaaggc
     9721 agattccttc gaaagtgggg ccggccggag ccacccatcg tccctctcgc ggcccagccg
     9781 tgctgtgctg gcgccaagct ccccgccggc ctcccacccg ctcctccgcg tcctcagctc
     9841 actcctctgc tcccaggtgg ccccagtcct caccccacct cgcttggact ccccacttcc
     9901 tgcccatcgt ccgctgttgg gagaccctct ccctgacccc agggactgct gaggcagcct
     9961 ccaagcctcc cagtgtcccc gaggctgccc ctagaagctg gcttggggct gtaccaaaag
    10021 gtcacccaca gtcccactcc aaggcaggct tgactagcag ggatctcagg gtgcccatgg
    10081 atcaagacta agctagagtg ggtcctcagg ccgaggctaa gctaggtgtg cctccaggtc
    10141 tcctgccagg gggctgagaa tttctaaacc cgggtggctg tgacccctag gcagagccag
    10201 cccagccctt gccagggatg gagaccacct cgaggaggcc aagccctggg ggtccacagg
    10261 cctgtgggct tcggggaggc tctgctccct gtgcctgtgt ggcccaggct gctgagtcat
    10321 cagaacctcg ggggccgcgc gggccccaca ttccgcccag gcctctctct gacccccttc
    10381 ccagcccatc tgtgtttttg gaaaacagag ccagagcccc cgcggccctg ccagcttgcg
    10441 gctgctcacg ctgggactca aatcgcaccc ttctgtcttc aaagtccacc ttcacttcaa
    10501 agctcggtcc caccccagcc cggcctccac agggccacca cctgcccaca cccaggcccg
    10561 ctgctgccca gtttcggagg gaccttgggc atcccctgat cctctctaga gcgcggggtt
    10621 cctggcatgg gcccgttaca catgggtggc tcggtgggtg gtgaggacgg ggctgggaga
    10681 agatcctggg gaccccatgg tggaggcaat gaggcaccca aaccccaact ccagcgatgg
    10741 ctgcttccac ggccctccga gccctgacct tcaaggtgcg aagcttcagg ggcaggggtg
    10801 agtggaaggt gggcttcctc ccttgccacc tggggggcgg gccaggacag atgctccgtg
    10861 agagcacttc caacctaggc ccagctgtgg ggaaggaggg agcaggcggc tgggctccag
    10921 gcagggggaa gagttgcctg agaactcagg gagagaggga gggctgggca ccccatgcca
    10981 gctccagctg cagcaccaga gctcagagca gaggaggcag gagccagcag gctgggaggc
    11041 ttcctggagg aggtgtccca ggcccctgcc agcactgcag ccttgagcac gaggccacgc
    11101 tgggctcctg cttccagggc cgcagaccca gcccagcact gcccatgctg cccttgccag
    11161 ggacccttac agagctagca cctgggtccc tccccctggc tgggcatggg ctggtctcga
    11221 caacaaagaa ggggtagctg tggcctcaag gtctacaaca ggttgtgatc tgtgggtgcc
    11281 aagaagtcat gggccctcag catcctcagg gccagtgagt gtccacctgg gccagtgtgg
    11341 ggctgaaggg tgagagctga gaggcggggc tgacatcctg gctctgctgc cagtggctgt
    11401 gtggccttgg gaaagtcact tagcatctct gggccttggt ttcctcatcc atcagaaggg
    11461 aaccaaagaa ggccctgcct gcctcagctg tggatggtgt agctcagtgt tgtctgtgag
    11521 aggaaggccc ttcggcagcc gcgcctctgg cttcagtaca cccgtgagct gctttctgtg
    11581 cccaggcctt caaatcacgg ggacagcccg tgggtgtggt tcagggcctg ggcaccacag
    11641 gcaaggggaa gctgacatgt ccctccgtgg gaagtggcag tccccatggc taccgggcat
    11701 cacagggcgt ttggaaggga ccctggaggg aggagcagct cctcgaggga ggagcccggg
    11761 gctggggtac ggaggcctct gcacatctta gagtaaaaca aagcaggaga ggctgggtgc
    11821 ggtggctcat gcctataatc ccagcacttt aggaggctga ggcgggcaga tcacctgagg
    11881 tcgggagttc aagaccagcc tgaccacagg gagaaacccc atctttacta aaactacaaa
    11941 attagctggg tgtggtggca catgcctgta atcccagata ttcgggaggc tgaggcagga
    12001 gaatcgcttg aacctgggaa gcagaggttg cgctgagccg agatggcacc attgcactcc
    12061 agcctgggca acgagagcga aactccgtct caaaaaaaca aaaacaaaaa aatcaaaaca
    12121 atcaaaaaaa caagcaggag gggctctgag gtgcctgcaa cacccaggta caatccgtgg
    12181 ccctgaggcc catcacaggg aaggggtctt tgcagctctt tcaaccccca gcccagcatc
    12241 caaggaagcc cagggcaggg agaaacctca gctgcaccat cagagctcag aacagagaag
    12301 gcagaaatta gcagggagtg gggctgggga ggcttcctag aagacgtgtc tcccgccttg
    12361 ctggcactga ggccttgaga tgggtccata ctgggccccc actgccaggg atgcagatcc
    12421 ggcccactgc tgaaatctgt gctcctggag cctccctcct gttcatgggc cacaggctgt
    12481 gaaaacccca gagtcctccc aggcagcaag ttttgttttg ttttttgttt gtttgcttgt
    12541 ttgttttttg agagtctgct cgtca
//