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url: https://zaoqu-liu.github.io/CellProgramMapper/
destination: docs
template:
bootstrap: 5
bootswatch: flatly
bslib:
primary: "#0d6efd"
border-radius: 0.5rem
btn-border-radius: 0.25rem
home:
title: CellProgramMapper
description: >
Projection of Single-Cell Transcriptomic Data onto Reference Gene Expression Programs
authors:
Zaoqu Liu:
href: https://github.com/Zaoqu-Liu
navbar:
structure:
left: [intro, reference, articles]
right: [search, github]
components:
articles:
text: Articles
menu:
- text: Getting Started
- text: Quick Start Guide
href: articles/quickstart.html
- text: "---"
- text: Algorithm & Theory
- text: Mathematical Framework
href: articles/algorithm.html
- text: NNLS Solver Details
href: articles/nnls-solver.html
- text: "---"
- text: Advanced Usage
- text: Building Custom References
href: articles/custom-reference.html
- text: Visualization Guide
href: articles/visualization.html
reference:
- title: Main Functions
desc: Core functions for mapping cells to gene expression programs
contents:
- CellProgramMapper
- get_usage
- get_scores
- print.CellProgramMapperResult
- summary.CellProgramMapperResult
- title: Reference Management
desc: Functions for managing reference datasets
contents:
- available_references
- load_reference
- download_reference
- get_reference_names
- title: Consensus Reference Building
desc: Build consensus GEPs from multiple cNMF results
contents:
- BuildConsensusReference
- cluster_geps
- pairwise_cluster_geps
- compute_gep_correlations
- get_top_genes_per_cgep
- merge_spectra
- merge_score_spectra
- write_consensus_results
- title: Scoring
desc: Compute add-on scores from usage matrix
contents:
- compute_scores
- compute_external_score
- create_score_definition
- create_score_data
- title: Seurat Integration
desc: Functions for Seurat object integration
contents:
- add_results_to_seurat
- is_seurat
- check_seurat_available
- get_seurat_version
- get_counts_from_seurat
- get_cells_from_seurat
- get_genes_from_seurat
- title: Data I/O
desc: Data input/output functions
contents:
- load_counts
- load_10x_mtx
- load_h5ad
- load_h5ad_hdf5r
- load_text_matrix
- load_tpm_stats
- save_results
- decompress_tar
- title: NMF Refitting
desc: Core NNLS solver functions
contents:
- fit_usage
- fit_usage_batched
- prepare_query
- scale_columns
- title: Utility Functions
desc: Helper functions for data manipulation
contents:
- row_sums
- col_sums
- normalize_rows
- is_integer_matrix
- is_nonnegative_matrix
- filter_na_genes
- aggregate_by_cluster
- ensure_dir
- get_cache_dir
- msg
- title: Internal
desc: Internal functions (not for direct use)
contents:
- CellProgramMapper-package
- consensus
- io
- mapper
- nmf_refit
- reference
- scoring
- seurat_compat
- utils
- zzz
footer:
structure:
left: developed_by
right: built_with