Hi,
I am running Dereplicator+ on an .MGF file derived from negative mode data. The input file contains negative charges, however, the results only show positive ion mode adducts.
I have reviewed the Dereplicator+ paper, which states:
"To assess the capability of DEREPLICATOR+ in identifying compounds in the negative ionization modes, we analyzed 341 additional spectra in the GNPS spectral library collected in the ESI (-) mode. DEREPLICATOR+ search correctly identified 88 (26%) of these compounds as top predictions (Supplementary Data 9)."
This statement suggests that Dereplicator+ is capable of analyzing data in negative ionization mode (ESI-).
Could you please provide guidance on how to address this issue and obtain correct adduct predictions for my negative mode data?
Thank you in advance.
Hi,
I am running Dereplicator+ on an .MGF file derived from negative mode data. The input file contains negative charges, however, the results only show positive ion mode adducts.
I have reviewed the Dereplicator+ paper, which states:
"To assess the capability of DEREPLICATOR+ in identifying compounds in the negative ionization modes, we analyzed 341 additional spectra in the GNPS spectral library collected in the ESI (-) mode. DEREPLICATOR+ search correctly identified 88 (26%) of these compounds as top predictions (Supplementary Data 9)."
This statement suggests that Dereplicator+ is capable of analyzing data in negative ionization mode (ESI-).
Could you please provide guidance on how to address this issue and obtain correct adduct predictions for my negative mode data?
Thank you in advance.