diff --git a/.github/trigger_files/beam_PreCommit_Yaml_Xlang_Direct.json b/.github/trigger_files/beam_PreCommit_Yaml_Xlang_Direct.json
index 616d37428c01..8c604b0a135c 100644
--- a/.github/trigger_files/beam_PreCommit_Yaml_Xlang_Direct.json
+++ b/.github/trigger_files/beam_PreCommit_Yaml_Xlang_Direct.json
@@ -1,4 +1,4 @@
 {
     "comment": "Modify this file in a trivial way to cause this test suite to run",
-    "revision": 1
+    "revision": 2
 }
diff --git a/.github/workflows/beam_PreCommit_Yaml_Xlang_Direct.yml b/.github/workflows/beam_PreCommit_Yaml_Xlang_Direct.yml
index 34a1af741f74..21281b8cd3e5 100644
--- a/.github/workflows/beam_PreCommit_Yaml_Xlang_Direct.yml
+++ b/.github/workflows/beam_PreCommit_Yaml_Xlang_Direct.yml
@@ -91,7 +91,7 @@ jobs:
       - name: run PreCommit Yaml Xlang Direct script
         uses: ./.github/actions/gradle-command-self-hosted-action
         with:
-          gradle-command: :sdks:python:yamlIntegrationTests -PbeamPythonExtra=ml_test,yaml
+          gradle-command: :sdks:python:yamlIntegrationTests -PbeamPythonExtra=p310_ml_test,yaml
       - name: Archive Python Test Results
         uses: actions/upload-artifact@v7
         if: failure()
diff --git a/buildSrc/src/main/groovy/org/apache/beam/gradle/BeamModulePlugin.groovy b/buildSrc/src/main/groovy/org/apache/beam/gradle/BeamModulePlugin.groovy
index 5ca0de9de846..766c72057327 100644
--- a/buildSrc/src/main/groovy/org/apache/beam/gradle/BeamModulePlugin.groovy
+++ b/buildSrc/src/main/groovy/org/apache/beam/gradle/BeamModulePlugin.groovy
@@ -3137,15 +3137,13 @@ class BeamModulePlugin implements Plugin<Project> {
           def distTarBall = "${pythonRootDir}/build/apache-beam.tar.gz"
           def packages = "gcp,test,aws,azure,dataframe"
           def extra = project.findProperty('beamPythonExtra')
+          def installTargets = "${distTarBall}[${packages}]"
+          if (extra) {
+            installTargets = "${distTarBall}[${packages},${extra}]"
+          }
           project.exec {
             executable 'sh'
-            args '-c', ". ${project.ext.envdir}/bin/activate && pip install --pre --retries 10 ${distTarBall}[${packages}]"
-          }
-          if (extra) {
-            project.exec {
-              executable 'sh'
-              args '-c', ". ${project.ext.envdir}/bin/activate && pip install --pre --retries 10 ${distTarBall}[${extra}]"
-            }
+            args '-c', ". ${project.ext.envdir}/bin/activate && pip install uv && uv pip install --pre ${installTargets}"
           }
         }
       }
diff --git a/sdks/python/apache_beam/yaml/integration_tests.py b/sdks/python/apache_beam/yaml/integration_tests.py
index 2d0b2787fc9b..150c0ca86254 100644
--- a/sdks/python/apache_beam/yaml/integration_tests.py
+++ b/sdks/python/apache_beam/yaml/integration_tests.py
@@ -790,6 +790,11 @@ def test(self, providers=providers):  # default arg to capture loop value
     yield f'test_{suffix}', test
 
 
+_SICKBAY_TESTS = {
+    'ml_transform.yaml': 'Requires broken TFT dependency types (e.g. ScaleTo01)',
+}
+
+
 def parse_test_files(filepattern):
   """Parses YAML test files and dynamically creates test cases.
 
@@ -810,13 +815,18 @@ def parse_test_files(filepattern):
   """
   for path in glob.glob(filepattern):
     with open(path) as fin:
-      suite_name = os.path.splitext(os.path.basename(path))[0].title().replace(
+      filename = os.path.basename(path)
+      suite_name = os.path.splitext(filename)[0].title().replace(
           '-', '') + 'Test'
       print(path, suite_name)
       methods = dict(
           create_test_methods(
               yaml.load(fin, Loader=yaml_transform.SafeLineLoader)))
-      globals()[suite_name] = type(suite_name, (unittest.TestCase, ), methods)
+      suite_class = type(suite_name, (unittest.TestCase, ), methods)
+      if filename in _SICKBAY_TESTS:
+        suite_class = unittest.skip(f"Sickbayed: {_SICKBAY_TESTS[filename]}")(
+            suite_class)
+      globals()[suite_name] = suite_class
 
 
 # Logging setups