diff --git a/setup.py b/setup.py
index ee5848eb6..1c715b791 100644
--- a/setup.py
+++ b/setup.py
@@ -30,7 +30,7 @@
     install_requires=[
         'astroquery>=0.4.1',
         'astroplan==0.8',
-        'astropy==4.2.1',
+        'astropy==5.1.1',
         'beautifulsoup4~=4.9',
         'django~=3.1',  # TOM Toolkit requires db math functions
         'djangorestframework~=3.12',