diff --git a/.changeset/angry-bears-count.md b/.changeset/angry-bears-count.md
new file mode 100644
index 0000000000..453ea41912
--- /dev/null
+++ b/.changeset/angry-bears-count.md
@@ -0,0 +1,8 @@
+---
+"@cloudflare/workers-utils": minor
+"wrangler": minor
+---
+
+Add production_enabled and previews_enabled support for custom domain routes
+
+Custom domain routes can now include optional production_enabled and previews_enabled boolean fields to control whether a domain serves production and/or preview traffic. When omitted, the API defaults apply (production enabled, previews disabled).
diff --git a/packages/workers-utils/src/config/environment.ts b/packages/workers-utils/src/config/environment.ts
index b9a0cf70a0..dd2ccb4ba8 100644
--- a/packages/workers-utils/src/config/environment.ts
+++ b/packages/workers-utils/src/config/environment.ts
@@ -20,7 +20,12 @@ export type ZoneNameRoute = {
 	zone_name: string;
 	custom_domain?: boolean;
 };
-export type CustomDomainRoute = { pattern: string; custom_domain: boolean };
+export type CustomDomainRoute = {
+	pattern: string;
+	custom_domain: boolean;
+	enabled?: boolean;
+	previews_enabled?: boolean;
+};
 export type Route =
 	| SimpleRoute
 	| ZoneIdRoute
diff --git a/packages/workers-utils/src/config/validation.ts b/packages/workers-utils/src/config/validation.ts
index e60ca0de7c..bf3241972e 100644
--- a/packages/workers-utils/src/config/validation.ts
+++ b/packages/workers-utils/src/config/validation.ts
@@ -964,8 +964,6 @@ function isValidRouteValue(item: unknown): boolean {
 			return false;
 		}
 
-		const otherKeys = Object.keys(item).length - 1; // minus one to subtract "pattern"
-
 		const hasZoneId =
 			hasProperty(item, "zone_id") && typeof item.zone_id === "string";
 		const hasZoneName =
@@ -973,13 +971,38 @@ function isValidRouteValue(item: unknown): boolean {
 		const hasCustomDomainFlag =
 			hasProperty(item, "custom_domain") &&
 			typeof item.custom_domain === "boolean";
+		const hasEnabled =
+			hasProperty(item, "enabled") && typeof item.enabled === "boolean";
+		const hasPreviewsEnabled =
+			hasProperty(item, "previews_enabled") &&
+			typeof item.previews_enabled === "boolean";
+
+		const recognizedKeys = [
+			hasZoneId,
+			hasZoneName,
+			hasCustomDomainFlag,
+			hasEnabled,
+			hasPreviewsEnabled,
+		].filter(Boolean).length;
+		const otherKeys = Object.keys(item).length - 1; // minus one to subtract "pattern"
 
-		if (otherKeys === 2 && hasCustomDomainFlag && (hasZoneId || hasZoneName)) {
-			return true;
-		} else if (
-			otherKeys === 1 &&
-			(hasZoneId || hasZoneName || hasCustomDomainFlag)
-		) {
+		// All keys must be recognized
+		if (recognizedKeys !== otherKeys) {
+			return false;
+		}
+
+		// zone_id and zone_name are mutually exclusive
+		if (hasZoneId && hasZoneName) {
+			return false;
+		}
+
+		// enabled and previews_enabled are only valid on custom domain routes
+		if ((hasEnabled || hasPreviewsEnabled) && !hasCustomDomainFlag) {
+			return false;
+		}
+
+		// Must have at least one of: zone_id, zone_name, or custom_domain
+		if (hasZoneId || hasZoneName || hasCustomDomainFlag) {
 			return true;
 		}
 	}
@@ -1030,7 +1053,7 @@ function mutateEmptyStringRouteValue(
 const isRoute: ValidatorFn = (diagnostics, field, value) => {
 	if (value !== undefined && !isValidRouteValue(value)) {
 		diagnostics.errors.push(
-			`Expected "${field}" to be either a string, or an object with shape { pattern, custom_domain, zone_id | zone_name }, but got ${JSON.stringify(
+			`Expected "${field}" to be either a string, or an object with shape { pattern, custom_domain, zone_id | zone_name, enabled, previews_enabled }, but got ${JSON.stringify(
 				value
 			)}.`
 		);
@@ -1060,7 +1083,7 @@ const isRouteArray: ValidatorFn = (diagnostics, field, value) => {
 	}
 	if (invalidRoutes.length > 0) {
 		diagnostics.errors.push(
-			`Expected "${field}" to be an array of either strings or objects with the shape { pattern, custom_domain, zone_id | zone_name }, but these weren't valid: ${JSON.stringify(
+			`Expected "${field}" to be an array of either strings or objects with the shape { pattern, custom_domain, zone_id | zone_name, enabled, previews_enabled }, but these weren't valid: ${JSON.stringify(
 				invalidRoutes,
 				null,
 				2
diff --git a/packages/workers-utils/src/construct-wrangler-config.ts b/packages/workers-utils/src/construct-wrangler-config.ts
index 1fc29d267a..fc29cf3709 100644
--- a/packages/workers-utils/src/construct-wrangler-config.ts
+++ b/packages/workers-utils/src/construct-wrangler-config.ts
@@ -70,6 +70,9 @@ function convertWorkerToWranglerConfig(config: APIWorkerConfig): RawConfig {
 			pattern: c.hostname as string,
 			zone_name: c.zone_name,
 			custom_domain: true,
+			enabled: (c as typeof c & { enabled: boolean }).enabled,
+			previews_enabled: (c as typeof c & { previews_enabled: boolean })
+				.previews_enabled,
 		})),
 	];
 
diff --git a/packages/workers-utils/tests/config/validation/normalize-and-validate-config.test.ts b/packages/workers-utils/tests/config/validation/normalize-and-validate-config.test.ts
index 33042d2600..ed391edaae 100644
--- a/packages/workers-utils/tests/config/validation/normalize-and-validate-config.test.ts
+++ b/packages/workers-utils/tests/config/validation/normalize-and-validate-config.test.ts
@@ -1164,9 +1164,9 @@ describe("normalizeAndValidateConfig()", () => {
 			expect(diagnostics.hasWarnings()).toBe(false);
 			expect(diagnostics.renderErrors()).toMatchInlineSnapshot(`
 				"Processing wrangler configuration:
-				  - Expected "route" to be either a string, or an object with shape { pattern, custom_domain, zone_id | zone_name }, but got 888.
+				  - Expected "route" to be either a string, or an object with shape { pattern, custom_domain, zone_id | zone_name, enabled, previews_enabled }, but got 888.
 				  - Expected "account_id" to be of type string but got 222.
-				  - Expected "routes" to be an array of either strings or objects with the shape { pattern, custom_domain, zone_id | zone_name }, but these weren't valid: [
+				  - Expected "routes" to be an array of either strings or objects with the shape { pattern, custom_domain, zone_id | zone_name, enabled, previews_enabled }, but these weren't valid: [
 				      666,
 				      777,
 				      {
@@ -5913,9 +5913,9 @@ describe("normalizeAndValidateConfig()", () => {
 				"Processing wrangler configuration:
 
 				  - "env.ENV1" environment configuration
-				    - Expected "route" to be either a string, or an object with shape { pattern, custom_domain, zone_id | zone_name }, but got 888.
+				    - Expected "route" to be either a string, or an object with shape { pattern, custom_domain, zone_id | zone_name, enabled, previews_enabled }, but got 888.
 				    - Expected "account_id" to be of type string but got 222.
-				    - Expected "routes" to be an array of either strings or objects with the shape { pattern, custom_domain, zone_id | zone_name }, but these weren't valid: [
+				    - Expected "routes" to be an array of either strings or objects with the shape { pattern, custom_domain, zone_id | zone_name, enabled, previews_enabled }, but these weren't valid: [
 				        666,
 				        777
 				      ].
diff --git a/packages/wrangler/src/__tests__/deploy/helpers.ts b/packages/wrangler/src/__tests__/deploy/helpers.ts
index 40eaaec572..d4e65004ed 100644
--- a/packages/wrangler/src/__tests__/deploy/helpers.ts
+++ b/packages/wrangler/src/__tests__/deploy/helpers.ts
@@ -215,6 +215,8 @@ export function mockCustomDomainsChangesetRequest({
 							environment: params.envName,
 							zone_name: "",
 							zone_id: "",
+							enabled: true,
+							previews_enabled: false,
 						};
 					}),
 					removed: [],
@@ -247,7 +249,11 @@ export function mockPublishCustomDomainsRequest({
 		override_existing_dns_record: boolean;
 	};
 	domains: Array<
-		{ hostname: string } & ({ zone_id?: string } | { zone_name?: string })
+		{
+			hostname: string;
+			enabled?: boolean;
+			previews_enabled?: boolean;
+		} & ({ zone_id?: string } | { zone_name?: string })
 	>;
 	env?: string | undefined;
 	useServiceEnvironments?: boolean | undefined;
diff --git a/packages/wrangler/src/__tests__/deploy/routes.test.ts b/packages/wrangler/src/__tests__/deploy/routes.test.ts
index fd95c5b3ee..dea7e76906 100644
--- a/packages/wrangler/src/__tests__/deploy/routes.test.ts
+++ b/packages/wrangler/src/__tests__/deploy/routes.test.ts
@@ -654,6 +654,44 @@ describe("deploy", () => {
 				expect(std.out).toContain("api.example.com (custom domain)");
 			});
 
+			it("should pass enabled and previews_enabled to the custom domains API", async ({
+				expect,
+			}) => {
+				writeWranglerConfig({
+					routes: [
+						{
+							pattern: "api.example.com",
+							custom_domain: true,
+							enabled: true,
+							previews_enabled: true,
+						},
+					],
+				});
+				writeWorkerSource();
+				mockUpdateWorkerSubdomain({ enabled: false });
+				mockUploadWorkerRequest({ expectedType: "esm" });
+				mockGetZones("api.example.com", [{ id: "api-example-com-id" }]);
+				mockGetZoneWorkerRoutes("api-example-com-id", []);
+				mockCustomDomainsChangesetRequest({});
+				mockPublishCustomDomainsRequest({
+					publishFlags: {
+						override_scope: true,
+						override_existing_origin: false,
+						override_existing_dns_record: false,
+					},
+					domains: [
+						{
+							hostname: "api.example.com",
+							enabled: true,
+							previews_enabled: true,
+						},
+					],
+				});
+				await runWrangler("deploy ./index");
+				expect(std.out).toContain("api.example.com (custom domain)");
+				expect(std.out).toContain("[enabled, previews: enabled]");
+			});
+
 			it("should confirm override if custom domain deploy would override an existing domain", async ({
 				expect,
 			}) => {
@@ -677,6 +715,8 @@ describe("deploy", () => {
 							hostname: "api.example.com",
 							service: "test-name",
 							environment: "",
+							enabled: true,
+							previews_enabled: false,
 						},
 					],
 				});
@@ -687,6 +727,8 @@ describe("deploy", () => {
 					hostname: "api.example.com",
 					service: "other-script",
 					environment: "",
+					enabled: true,
+					previews_enabled: false,
 				});
 				mockPublishCustomDomainsRequest({
 					publishFlags: {
@@ -729,6 +771,8 @@ Update them to point to this script instead?`,
 							hostname: "api.example.com",
 							service: "test-name",
 							environment: "",
+							enabled: true,
+							previews_enabled: false,
 						},
 					],
 				});
@@ -773,6 +817,8 @@ Update them to point to this script instead?`,
 							hostname: "api.example.com",
 							service: "test-name",
 							environment: "",
+							enabled: true,
+							previews_enabled: false,
 						},
 					],
 					dnsRecordConflicts: [
@@ -783,6 +829,8 @@ Update them to point to this script instead?`,
 							hostname: "api.example.com",
 							service: "test-name",
 							environment: "",
+							enabled: true,
+							previews_enabled: false,
 						},
 					],
 				});
@@ -793,6 +841,8 @@ Update them to point to this script instead?`,
 					hostname: "api.example.com",
 					service: "other-script",
 					environment: "",
+					enabled: true,
+					previews_enabled: false,
 				});
 				mockPublishCustomDomainsRequest({
 					publishFlags: {
@@ -874,6 +924,8 @@ Update them to point to this script instead?`,
 							hostname: "api.example.com",
 							service: "test-name",
 							environment: "",
+							enabled: true,
+							previews_enabled: false,
 						},
 					],
 				});
@@ -884,6 +936,8 @@ Update them to point to this script instead?`,
 					hostname: "api.example.com",
 					service: "other-script",
 					environment: "",
+					enabled: true,
+					previews_enabled: false,
 				});
 				mockConfirm({
 					text: `Custom Domains already exist for these domains:
diff --git a/packages/wrangler/src/deploy/deploy.ts b/packages/wrangler/src/deploy/deploy.ts
index 03c7b8fc30..ea69235bdc 100644
--- a/packages/wrangler/src/deploy/deploy.ts
+++ b/packages/wrangler/src/deploy/deploy.ts
@@ -152,6 +152,8 @@ export type CustomDomain = {
 	hostname: string;
 	service: string;
 	environment: string;
+	enabled: boolean;
+	previews_enabled: boolean;
 };
 type UpdatedCustomDomain = CustomDomain & { modified: boolean };
 type ConflictingCustomDomain = CustomDomain & {
@@ -248,6 +250,21 @@ export function renderRoute(route: Route): string {
 		} else if ("zone_name" in route) {
 			result += ` (zone name: ${route.zone_name})`;
 		}
+
+		if (isCustomDomain) {
+			const flags: string[] = [];
+			if ("enabled" in route && route.enabled !== undefined) {
+				flags.push(route.enabled ? "enabled" : "disabled");
+			}
+			if ("previews_enabled" in route && route.previews_enabled !== undefined) {
+				flags.push(
+					route.previews_enabled ? "previews: enabled" : "previews: disabled"
+				);
+			}
+			if (flags.length > 0) {
+				result += ` [${flags.join(", ")}]`;
+			}
+		}
 	}
 	return result;
 }
@@ -286,6 +303,11 @@ export async function publishCustomDomains(
 			hostname: domainRoute.pattern,
 			zone_id: "zone_id" in domainRoute ? domainRoute.zone_id : undefined,
 			zone_name: "zone_name" in domainRoute ? domainRoute.zone_name : undefined,
+			enabled: "enabled" in domainRoute ? domainRoute.enabled : undefined,
+			previews_enabled:
+				"previews_enabled" in domainRoute
+					? domainRoute.previews_enabled
+					: undefined,
 		};
 	});
 
diff --git a/packages/wrangler/src/utils/download-worker-config.ts b/packages/wrangler/src/utils/download-worker-config.ts
index c3562ac292..3902f12b1f 100644
--- a/packages/wrangler/src/utils/download-worker-config.ts
+++ b/packages/wrangler/src/utils/download-worker-config.ts
@@ -17,6 +17,8 @@ type CustomDomainsRes = {
 	service: string;
 	environment: string;
 	cert_id: string;
+	enabled: boolean;
+	previews_enabled: boolean;
 }[];
 
 type WorkerSubdomainRes = {