## LoL 1. On which protein is the first ChIP-Seq is performed? 1. In ChIP-Seq, what factors contribute to a spurious peak? What experimental/computational procedures can you take to reduce such noises? 1. How is a TF-binding motif represented computationally? How can you use this representation to interrogate observed sequence reads? 1. What are the necessary and essential conditions for a gene to be transcribed? 1. List experiment techniques to interrogate * RNAPII activity * Ribosome activity * DNA methylation * Chromatin Accessibility * Histone modification * TF binding-site * ncRNA effect site
LoL
On which protein is the first ChIP-Seq is performed?
In ChIP-Seq, what factors contribute to a spurious peak? What experimental/computational procedures can you take to reduce such noises?
How is a TF-binding motif represented computationally? How can you use this representation to interrogate observed sequence reads?
What are the necessary and essential conditions for a gene to be transcribed?
List experiment techniques to interrogate