diff --git a/requirements_dev.txt b/requirements_dev.txt
index 8b83ccb..98ebf9b 100644
--- a/requirements_dev.txt
+++ b/requirements_dev.txt
@@ -1,7 +1,7 @@
 anndata>=0.7.8
 bump2version==0.5.11
 coverage==4.5.4
-flake8==3.7.8
+flake8==4.0.1
 h5py>=2.10.0
 igraph>=0.9.9
 louvain>=0.6.1