diff --git a/src/Analyser/MutatingScope.php b/src/Analyser/MutatingScope.php
index 79d4be017b..64e4607473 100644
--- a/src/Analyser/MutatingScope.php
+++ b/src/Analyser/MutatingScope.php
@@ -2869,7 +2869,7 @@ public function invalidateExpression(Expr $expressionToInvalidate, bool $require
 				continue;
 			}
 			$firstExpr = $holders[array_key_first($holders)]->getTypeHolder()->getExpr();
-			if ($this->shouldInvalidateExpression($exprStringToInvalidate, $expressionToInvalidate, $firstExpr, $this->getNodeKey($firstExpr), false, $invalidatingClass)) {
+			if ($this->shouldInvalidateExpression($exprStringToInvalidate, $expressionToInvalidate, $firstExpr, $this->getNodeKey($firstExpr), $requireMoreCharacters, $invalidatingClass)) {
 				$invalidated = true;
 				continue;
 			}
diff --git a/tests/PHPStan/Analyser/nsrt/bug-14545.php b/tests/PHPStan/Analyser/nsrt/bug-14545.php
new file mode 100644
index 0000000000..e12b2e9df1
--- /dev/null
+++ b/tests/PHPStan/Analyser/nsrt/bug-14545.php
@@ -0,0 +1,112 @@
+<?php
+
+declare(strict_types = 1);
+
+namespace Bug14545;
+
+use function PHPStan\Testing\assertType;
+
+interface SomeInterface {
+	public function test(): void;
+}
+
+class ObjectClass {
+}
+
+class OtherClass {
+}
+
+/**
+ * @template T of object
+ * @param class-string<T> $class_name
+ * @return T
+ */
+function getObject1(string $class_name): object {
+	return new $class_name;
+}
+
+function testStoredInstanceofWithGenericMethodCall(): void {
+	$obj = getObject1(ObjectClass::class);
+	$is_interface = $obj instanceof SomeInterface;
+	if($is_interface) {
+		assertType('Bug14545\ObjectClass&Bug14545\SomeInterface', $obj);
+		$obj->test();
+	}
+
+	if($is_interface) {
+		assertType('Bug14545\ObjectClass&Bug14545\SomeInterface', $obj);
+		$obj->test();
+	}
+}
+
+function testStoredInstanceofWithGenericFuncCall(): void {
+	$obj = getObject1(ObjectClass::class);
+	$is_interface = $obj instanceof SomeInterface;
+	if($is_interface) {
+		var_dump($obj);
+	}
+
+	if($is_interface) {
+		assertType('Bug14545\ObjectClass&Bug14545\SomeInterface', $obj);
+	}
+}
+
+function testStoredInstanceofWithConcreteClass(): void {
+	$obj = getObject1(OtherClass::class);
+	$is_interface = $obj instanceof SomeInterface;
+	if($is_interface) {
+		assertType('Bug14545\OtherClass&Bug14545\SomeInterface', $obj);
+		$obj->test();
+	}
+
+	if($is_interface) {
+		assertType('Bug14545\OtherClass&Bug14545\SomeInterface', $obj);
+	}
+}
+
+function getObject2(): object {
+	return new \stdClass();
+}
+
+function testStoredInstanceofWithAbstractObject(): void {
+	$obj = getObject2();
+	$is_interface = $obj instanceof SomeInterface;
+	if($is_interface) {
+		assertType('Bug14545\SomeInterface', $obj);
+		$obj->test();
+	}
+
+	if($is_interface) {
+		assertType('Bug14545\SomeInterface', $obj);
+		$obj->test();
+	}
+}
+
+function testThreeConsecutiveChecks(): void {
+	$obj = getObject1(ObjectClass::class);
+	$is_interface = $obj instanceof SomeInterface;
+	if($is_interface) {
+		$obj->test();
+	}
+	if($is_interface) {
+		$obj->test();
+	}
+	if($is_interface) {
+		assertType('Bug14545\ObjectClass&Bug14545\SomeInterface', $obj);
+	}
+}
+
+/**
+ * @param array<mixed, mixed> $data
+ */
+function testStoredIsArray(array $data): void {
+	$value = $data['key'] ?? null;
+	$isArray = is_array($value);
+	if ($isArray) {
+		assertType('array<mixed, mixed>', $value);
+		var_dump($value);
+	}
+	if ($isArray) {
+		assertType('array<mixed, mixed>', $value);
+	}
+}