diff --git a/packages/react-native-gesture-handler/src/v3/hooks/callbacks/useReanimatedEventHandler.ts b/packages/react-native-gesture-handler/src/v3/hooks/callbacks/useReanimatedEventHandler.ts
index 77d9b12d86..76e98c4f70 100644
--- a/packages/react-native-gesture-handler/src/v3/hooks/callbacks/useReanimatedEventHandler.ts
+++ b/packages/react-native-gesture-handler/src/v3/hooks/callbacks/useReanimatedEventHandler.ts
@@ -1,4 +1,4 @@
-import { useMemo } from 'react';
+import { useEffect, useMemo, useRef } from 'react';
 
 import type { ReanimatedHandler } from '../../../handlers/gestures/reanimatedWrapper';
 import { Reanimated } from '../../../handlers/gestures/reanimatedWrapper';
@@ -10,6 +10,12 @@ import type {
 } from '../../types';
 import { eventHandler } from './eventHandler';
 
+const REANIMATED_EVENT_NAMES = [
+  'onGestureHandlerReanimatedEvent',
+  'onGestureHandlerReanimatedStateChange',
+  'onGestureHandlerReanimatedTouchEvent',
+];
+
 const workletNOOP = () => {
   'worklet';
   // no-op
@@ -59,14 +65,24 @@ export function useReanimatedEventHandler<
     );
   };
 
+  // Fast Refresh invalidates `useMemo` caches but preserves `useRef`, so the
+  // `handlerTag` computed with `useMemo([])` in `useGesture` can regenerate
+  // on FR. Without forcing a rebuild, the registered worklet keeps the old
+  // `handlerTag` in its closure and `isEventForHandlerWithTag` rejects every
+  // event emitted by the freshly-created native handler.
+  const prevHandlerTagRef = useRef(handlerTag);
+  const handlerTagChanged = prevHandlerTagRef.current !== handlerTag;
+
+  // Write after commit so interrupted or re-invoked renders don't desync the
+  // ref from what was actually committed.
+  useEffect(() => {
+    prevHandlerTagRef.current = handlerTag;
+  }, [handlerTag]);
+
   const reanimatedEvent = Reanimated?.useEvent(
     callback,
-    [
-      'onGestureHandlerReanimatedEvent',
-      'onGestureHandlerReanimatedStateChange',
-      'onGestureHandlerReanimatedTouchEvent',
-    ],
-    !!reanimatedHandler?.doDependenciesDiffer
+    REANIMATED_EVENT_NAMES,
+    handlerTagChanged || !!reanimatedHandler?.doDependenciesDiffer
   );
 
   return reanimatedEvent;