An R/Bioconductor package for the integrated analysis of pooled high-throughput CRISPR/Cas9 or shRNA screening experiments.
The initial version of this package was created at Genentech, inc. and was extended by the team at Maze Therapeutics. Current maintenance, development, and extension is supervised by the team at Eikon Therapeutics.
See vignettes for examples of screen design, processing, analysis, and integration.