Added option to supply 100x2 matrix for custom bias#85
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bfairkun wants to merge 1 commit intoalyssafrazee:masterfrom
Open
Added option to supply 100x2 matrix for custom bias#85bfairkun wants to merge 1 commit intoalyssafrazee:masterfrom
bfairkun wants to merge 1 commit intoalyssafrazee:masterfrom
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Thanks for this nice tool. I was interested in changing the bias from which fragments are generated to better simulate how lower-quality RNA generates RNA-seq with a stronger 3' bias (https://bmcbioinformatics.biomedcentral.com/articles/10.1186/s12859-016-0922-z)... So the proposed change allows users to specify their own 100x2 dataframe (instead of reading in the
cdna_pos_bias.csvorrnaf_pos_bias.csv) which they can generate however they please... For example, here is a plot of thecdna_pos_bias.csvandrnaf_pos_bias.csvdata, as well as some other similar 100x2 dataframes I created from beta distribution (eg from thedbetabase R function).