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Scripting utility for AMBER Molecular Dynamics simulations. This bash script automates the generation of input files for multiple trajectories, handling the stages of minimization, heating, equilibration, and production with ligand constraints

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Molecular Dynamics Simulations with AMBER

In this repository, you'll find two shell scripts designed to perform Molecular Dynamics (MD) simulations using the AMBER suite of programs.

The first script, generate_amber_inputs.sh, creates the required input files for AMBER simulations. It enables the generation of multiple trajectories with ligand constraints specified by a range of residues.

The second script, run_md_simulations.sh, executes preproduction or production MD simulations on a specified system using the AMBER suite of programs.

To use these scripts, follow these steps:

  1. Generate the necessary input files by running generate_amber_inputs.sh with the desired parameters:

./generate_amber_inputs.sh [RESIDUE_START] [RESIDUE_END] [NUMBER_OF_TRAJECTORIES]

  1. Run the MD simulations by executing run_md_simulations.sh with the appropriate arguments:

./run_md_simulations.sh [SYSTEM NAME] [CPU] [0/1] [GPU INDEX] [MD Start] [MD Stop]

For more detailed instructions on how to use these scripts, please refer to the comments in each script.

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Scripting utility for AMBER Molecular Dynamics simulations. This bash script automates the generation of input files for multiple trajectories, handling the stages of minimization, heating, equilibration, and production with ligand constraints

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