Understanding and applying protein language models

This repository contains data for the practical session named above in the AI-driven approaches in structural biology India EMBO lecture course at IISc in May 2026.

Slides

Click here for the slides.

Google Colab Notebook

Data

References

1. Lin Z. et al. (2023) Science. Evolutionary-scale prediction of atomic-level protein structure with a language model. DOI
2. Meier J. et al. (2021) NeurIPS. Language models enable zero-shot prediction of the effects of mutations on protein function. PDF
3. Olsen TH et al. (2024) Bioinformatics, Addressing the antibody germline bias and its effect on language models for improved antibody design. DOI
4. Wikipedia