Skip to content

Draft dataset loader Xenium cervical cancer with pathology-based ground truth cell type annotation#41

Merged
rcannood merged 10 commits into
openproblems-bio:mainfrom
koenvandenberge:main
May 19, 2026
Merged

Draft dataset loader Xenium cervical cancer with pathology-based ground truth cell type annotation#41
rcannood merged 10 commits into
openproblems-bio:mainfrom
koenvandenberge:main

Conversation

@koenvandenberge

Copy link
Copy Markdown
Contributor

Describe your changes

Initial edits to add a dataset loader for the public Xenium cervical cancer dataset.

Checklist before requesting a review

  • [x ] I have performed a self-review of my code

  • Check the correct box. Does this PR contain:

    • Breaking changes
    • New functionality
    • Major changes
    • [ x] Minor changes
    • Bug fixes
  • Proposed changes are described in the CHANGELOG.md

  • CI Tests succeed and look good!

@koenvandenberge koenvandenberge changed the title Draft dataset loader Xenium cervical cancer Draft dataset loader Xenium cervical cancer with pathology-based ground truth cell type annotation May 19, 2026
rcannood and others added 5 commits May 19, 2026 11:47
Signed-off-by: Robrecht Cannoodt <rcannood@gmail.com>
Signed-off-by: Robrecht Cannoodt <rcannood@gmail.com>
Signed-off-by: Robrecht Cannoodt <rcannood@gmail.com>
Comment on lines +12 to +19
param_list:
- id: ...
input: s3://hca-op-spatial/datasets/gt_annotated_data/Xenium_Prime_Cervical_Cancer_FFPE_Aligned.zarr
dataset_name: ...
dataset_url: ...
dataset_summary: ...
dataset_description: ...
dataset_organism: ...

Copy link
Copy Markdown
Member

Choose a reason for hiding this comment

The reason will be displayed to describe this comment to others. Learn more.

@koenvandenberge Could you fill in this info?

Example from a different task:

  - id: tenx_visium/visium/human_colorectal_cancer
    input_expression: "https://cf.10xgenomics.com/samples/spatial-exp/2.0.1/CytAssist_11mm_FFPE_Human_Colorectal_Cancer/CytAssist_11mm_FFPE_Human_Colorectal_Cancer_filtered_feature_bc_matrix.h5"
    input_spatial: "https://cf.10xgenomics.com/samples/spatial-exp/2.0.1/CytAssist_11mm_FFPE_Human_Colorectal_Cancer/CytAssist_11mm_FFPE_Human_Colorectal_Cancer_spatial.tar.gz"
    dataset_name: 10X Visium - Human Colorectal Cancer
    dataset_summary: Gene expression library of Human Colorectal Cancer (CytAssist FFPE) using the Human Whole Transcriptome Probe Set
    dataset_description: "The tissue was sectioned as described in the Visium CytAssist Spatial Gene Expression for FFPE Tissue Preparation Guide (CG000518). Tissue section of 5 µm was placed on a standard glass slide, then stained following the Deparaffinization, H&E Staining, Imaging & Decrosslinking Demonstrated Protocol (CG000520). The glass slide with tissue section was processed via Visium CytAssist instrument to transfer analytes to a Visium CytAssist Spatial Gene Expression Slide v2, with 11 mm capture areas following the Visium CytAssist Spatial Gene Expression Reagent Kits User Guide (CG000495)."
    dataset_url: # url to dataset, if available
    dataset_reference_doi: # doi for dataset, if available
    dataset_organism: homo_sapiens

Copy link
Copy Markdown
Contributor Author

Choose a reason for hiding this comment

The reason will be displayed to describe this comment to others. Learn more.

Done, thanks for the pointers.

@rcannood rcannood left a comment

Copy link
Copy Markdown
Member

Choose a reason for hiding this comment

The reason will be displayed to describe this comment to others. Learn more.

Lgtm!

@rcannood rcannood merged commit ee2fc20 into openproblems-bio:main May 19, 2026
2 checks passed
Sign up for free to join this conversation on GitHub. Already have an account? Sign in to comment

Labels

None yet

Projects

None yet

Development

Successfully merging this pull request may close these issues.

2 participants