Chat with Open Targets genetics database leveraging text-to-graphQL capabilities of OpenAI Codex.
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May 16, 2025 - Python
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open-targets
Here are 14 public repositories matching this topic...
MCP server for Open Targets data
bioinformatics genomics mcp drug-discovery opentargets biomedical-data open-targets model-context-protocol mcp-server
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May 15, 2026 - Python
GeneticsGPT is an intuitive application that leverages OpenAI's GPT-3.5-turbo model to provide insights and answers to genetic and disease-related questions. By integrating with the Open Targets genetics database and translating natural language queries into GraphQL, it empowers users to easily explore and extract valuable information.
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Nov 2, 2025 - Python
Analyze human genetic knockouts to predict drug efficacy and side effects
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Apr 8, 2026 - Python
AI-powered biomarker discovery and explanation tool for the Open Targets Hackathon 2025
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Mar 5, 2026 - HTML
A wrapper template around the existing OpenTargets Genetics API allowing anyone to merge in their own data
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Jan 19, 2023 - TypeScript
Powerful Model Context Protocol (MCP) server for therapeutic discovery and drug repurposing using the Open Targets Platform GraphQL API.
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Apr 13, 2026 - Python
Unsupervised clustering of common human diseases based on GWAS and WGS data, with a focus on Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)
machine-learning gwas genetics hierarchical-clustering system-biology common-diseases open-targets chronic-fatigue-syndrome myalgic-encephalomyelitis post-gwas-analysis
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May 24, 2026 - R
Prescribing genes, not just drugs. ETL + dashboard pipeline that cross-references Open Targets, ChEMBL and UniProt to rank therapeutic targets by disease.
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Mar 25, 2026 - Python
Local research-only AI agent for evidence-grounded therapeutic target discovery with PubTator3, Open Targets, Neo4j, ChEMBL/RDKit, and FastAPI.
bioinformatics neo4j pubmed knowledge-graph drug-discovery rdkit pubtator chembl europe-pmc therapeutic-targets fastapi biomedical-literature ai-agent openalex open-targets
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Jun 6, 2026 - Python
Forensic post-mortems for clinical trials. Give it an NCT ID, drug, or target: it classifies why a trial stopped, links the biology across ClinicalTrials.gov, openFDA, Open Targets, and ChEMBL, and returns an evidence-graded report, or refuses to speculate when the stop was not scientific.
python cli bioinformatics computational-biology open-science drug-discovery clinical-trials chembl openfda pharmacovigilance rag llm open-targets clinicaltrials-gov
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Jun 4, 2026 - Python
Fixture-backed biomedical evidence atlas for browsing neuroplasticity and receptor pharmacology research, with a FastAPI backend and a React frontend.
react python bioinformatics typescript pharmacology pubmed chembl neuroplasticity fastapi evidence-synthesis clinicaltrials open-targets serotonin htr2a
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Jun 4, 2026 - Python
his repository contains a simple notebook for drug repurposing analysis based on disease–target association data obtained from the Open Targets Platform and bioactivity data from ChEMBL. The workflow identifies approved medicines potentially relevant for selected disease-associated targets.
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May 19, 2026 - Jupyter Notebook
AI-powered drug repurposing pipeline that federates live data across 8 biomedical databases in real time, ranks candidates via DeepSeek V4 LLM analysis, and visualizes target–drug–protein networks in an interactive 3D knowledge graph.
python open-source bioinformatics ai pubmed knowledge-graph drug-discovery drug-repurposing clinical-trials uniprot chembl openfda translational-research fastapi biomedical-research streamlit open-targets deepseek string-db neglected-diseases
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Jun 21, 2026 - Python
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